No packages match

HealthMarkers - Clinical and Metabolic Biomarker Calculation Toolkit

Computes specialist biomarker indices and risk scores for metabolic, cardiovascular, renal, hepatic, inflammatory, frailty, and psychiatric health assessment. Includes fasting and OGTT insulin sensitivity/resistance indices, ASCVD/QRISK3/KFRE risk equations, liver and kidney markers, frailty and comorbidity indices, biofluid marker panels, and utilities for column mapping, normalization, imputation, and combined marker dispatch.

Last updated

4.78 score 60 scripts 372 downloads

InsuSensCalc - Insulin Sensitivity Indices Calculator

Facilitates the calculation of 40 different insulin sensitivity indices based on fasting, oral glucose tolerance test (OGTT), lipid (adipose), tracer (palmitate and glycerol rate), and DXA (fat mass) measurement values. Enables easy and accurate assessment of insulin sensitivity, critical for understanding and managing metabolic disorders like diabetes and obesity. Indices calculated are described in Gastaldelli (2022) <doi:10.1002/oby.23503>, Suleman (2024) <doi:10.1210/clinem/dgae275>, and Lorenzo (2010) <doi:10.1210/jc.2010-1144>.

Last updated

4.48 score 2 stars 6 scripts 286 downloads

IsletCalc - Calculators for Insulin and Glucagon Release Indices

Facilitates the calculation of validated pancreatic islet hormone-release indices from fasting and oral glucose tolerance test (OGTT) measurements. Provides beta-cell insulin release indices (including HOMA-beta, corrected insulin response, Stumvoll first-phase index, BIGTT-AIR, and disposition indices) as described in Madsen (2024) <doi:10.1038/s42255-024-01140-6>, alongside alpha-cell glucagon release and glucagon resistance indices derived from the glucagon-suppression and liver-alpha-cell-axis literature. Enables reproducible assessment of beta-cell and alpha-cell function for metabolic and endocrine research.

Last updated

4.00 score 7 scripts 214 downloads